[轉載]中國研究人員在蝙蝠體內發現一批新型冠狀病毒

https://edition.cnn.com/2021/06/10/health/bats-coronavirus-china-genome/index.html

(以下採用google翻譯,可能存在字詞轉換錯誤,請以原文為準)
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更新时间 0346 GMT (1146 HKT) 2021 年 6 月 11 日

(美国有线电视新闻网)中国研究人员周四表示,他们在蝙蝠中发现了一批新型冠状病毒,其中一种可能在基因上与Covid-19病毒最接近。

据研究人员称,他们在中国西南部云南省的一个小地区的发现表明蝙蝠体内有多少冠状病毒,以及有多少有可能传播给人类。
山东大学的史伟峰及其同事在 2019 年 5 月至 2020 年 11 月期间从森林栖息的小型蝙蝠身上收集了样本。他们测试了尿液和粪便,并从蝙蝠的嘴里取出了拭子。

研究人员在发表在《细胞》杂志上的一份报告中写道:“我们总共组装了来自不同蝙蝠物种的 24 个新型冠状病毒基因组,其中包括四种类似 SARS-CoV-2 的冠状病毒 。”

他们说,其中一个在基因上与引起当前大流行的 SARS-CoV-2 病毒非常相似——一种名为 RpYN06 的病毒样本,取自一种名为 Rhinolophus pusillus 的马蹄蝠物种。

他们说,除了刺突蛋白的遗传差异外,它是最接近 SARS-CoV-2 的菌株,刺突蛋白是病毒附着在细胞上时使用的旋钮状结构。

“连同2020年6月从泰国采集的SARS-CoV-2相关病毒,这些结果清楚地表明,与SARS-CoV-2密切相关的病毒继续在蝙蝠种群中传播,并且在某些地区可能发生频率较高,“ 他们写。

研究人员正试图找出 SARS-CoV-2 的来源。虽然蝙蝠是一个可能的来源,但病毒也有可能感染了中间动物。导致 2002-2004 年爆发的 SARS 病毒被追踪到一种叫做果子狸的动物。

“蝙蝠是众所周知 的多种病毒的宿主宿主,这些病毒会导致人类严重疾病,并且与亨德拉病毒、马尔堡病毒、埃博拉病毒以及最显着的冠状病毒的外溢有关。除了蝙蝠和人类,冠状病毒还可以感染各种各样的家养和野生动物,包括猪、牛、老鼠、猫、狗、鸡、鹿和刺猬,”他们写道。

大多数样本来自马蹄蝠。2017 年,研究人员在云南的一个洞穴中取样,发现病毒在基因上与马蹄蝠中的 SARS 病毒非常接近。

周四报告中描述的三个样本在基因上也接近 SARS。

他们写道:“我们的研究突出了当地范围内蝙蝠冠状病毒的显着多样性,包括 SARS-CoV-2 和 SARS-CoV 的近亲。” 他们采样的蝙蝠物种在东南亚很常见,包括中国西南部、越南、老挝和其他地方。

尽管关于冠状病毒大流行的起源存在一些争议,但世界卫生组织的一份报告称,最有可能的来源是动物——可能是蝙蝠。

人们捕猎和吃蝙蝠,蝙蝠可以感染其他也被人类猎杀和吃掉的动物。当人们处理或屠宰动物时,病毒会感染人类。

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(CNN)Chinese researchers said Thursday they had found a batch of new coronaviruses in bats including one that may be the second-closest yet, genetically, to the Covid-19 virus.

According to the researchers, their discoveries in a single, small region of Yunnan province, southwestern China show just how many coronaviruses there are in bats and how many have the potential to spread to people.
Weifeng Shi of the University of Shandong and colleagues collected samples from small, forest-dwelling bats between May, 2019 and November, 2020. They tested urine and feces as well as taking swabs from the bats' mouths.

"In total, we assembled 24 novel coronavirus genomes from different bat species, including four SARS-CoV-2 like coronaviruses," the researchers wrote in a report published in the journal Cell.
One was very similar, genetically to the SARS-CoV-2 virus that's causing the current pandemic, they said -- a viral sample called RpYN06 taken from a horseshoe bat species called Rhinolophus pusillus.
It would be the closest strain to SARS-CoV-2 except for genetic differences on the spike protein, the knob-like structure that the virus uses when attaching to cells, they said.

"Together with the SARS-CoV-2 related virus collected from Thailand in June 2020, these results clearly demonstrate that viruses closely related to SARS-CoV-2 continue to circulate in bat populations, and in some regions might occur at a relatively high frequency," they wrote.

Researchers are trying to find where SARS-CoV-2 came from. Although a bat is a likely source, it's possible the virus infected an intermediary animal. The SARS virus that caused an outbreak in 2002-2004 was tracked to an animal called a civet cat.

"Bats are well known reservoir hosts for a variety of viruses that cause severe diseases in humans and have been associated with the spillovers of Hendra virus, Marburg virus, Ebola virus and, most notably, coronaviruses. Aside from bats and humans, coronaviruses can infect a wide range of domestic and wild animals, including pigs, cattle, mice, cats, dogs, chickens, deer and hedgehogs," they wrote.

Most of the samples came from species of horseshoe bats. In 2017, researchers sampling a cave in Yunnan found viruses very close genetically to the SARS virus in horseshoe bats.

Three of the samples described in Thursday's report were also close to SARS genetically.

"Our study highlights the remarkable diversity of bat coronaviruses at the local scale, including close relatives of both SARS-CoV-2 and SARS-CoV," they wrote. The bat species they sampled are common across Southeast Asia, including southwest China, Vietnam, Laos and elsewhere.

Although there's some controversy about the origin of the coronavirus pandemic, a World Health Organization report said the most likely source is an animal -- probably a bat.

People hunt and eat bats, and bats can infect other animals that are also hunted and eaten by people. Viruses can infect people when they handle or slaughter the animals.
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分享 2021-06-12

7 个评论

1. Rhinolophus ferrumequinum的生存范围遍及东亚,中亚,地中海,以及南欧地区。缘何在武汉传给人类?
2. 存在感染给人类的风险是现在才知道的吗。如果之前就知道为何现在才公布。之前不公布是为了什么?
3. 存在与sarscov2相近的株种,请科学论证此株种与sarscov2相互自然演变的可能性,以及自然演变所需的时间。
4. 论文数据的真实性未经查证
我當然是認為自然跨物種加抗生素演化出來的,但這不重要,重要的是用不擇手段把共匪政府這個本身造謠隱瞞的黃鼠狼炸出來給全世界看。
一句話,中間宿主在哪?
一句话,蝙蝠怎么到的武汉市中心,而且是在病毒所附近
山东大学的史伟峰及其同事在 2019 年 5 月至 2020 年 11 月期间从森林栖息的小型蝙蝠身上收集了样本。他们测试了尿液和粪便,并从蝙蝠的嘴里取出了拭子。

那之前不准联合国调查团进武汉是为什么?现在放出这种东西来有什么意义?
谁信不是求饶?

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王朔:中国最悲惨的事

一、好不容易建立新中国,结果新中国饿死的人比抗日战争牺牲的还多。
二、战死上千万同胞推翻中华民国,却发现国民党比共产党更人性文明。
三、发现当初的四大家族,其实还没有现在我党的处级干部有钱。
四、党官带领我们反美反西方,却发现他们的后代 全都移民美国了。
>> 1. Rhinolophus ferrumequinum的生存范围遍及东亚,中亚,地中海,以及...

跳到猪身上,自然演变就容易多了,蝙蝠+猪威力无边,看马来西亚以前的类似SARS病毒

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